Drug micro-containers smaller than a grain of sugar

Drug micro-containers smaller than a grain of sugar

tirsdag 15 aug 17

Kontakt

Anja Boisen
Professor
DTU Nanotech
45 25 57 27

Kontakt

Line Hagner Nielsen
Forsker
DTU Nanotech
45 25 57 51
At the research Centre of Excellence IDUN (Intelligent Drug delivery and Sensing Using micro-containers and Nanomechanics) at DTU headed by Professor Anja Boisen, a new type of tablet is under development, which may make the administering of drugs by the oral route more intelligent and effective.

It consists of a capsule like the ones known from current medicinal products. This capsule encapsulates the medicinal products to avoid any bad taste when the medicine is swallowed. The capsule is primarily made of gelatine which is dissolved in the stomach. Inside the gelatine capsule, there are hundreds of micro-containers each one smaller than a grain of sugar. It is therefore possible to carry hundreds of micro-containers on the tip of a finger. The drug is placed inside these small micro-containers.

IDUN

If the micro-containers are compared with sugar crystals (from the sugar bowl), it is evident that each and every container is only a fraction of the size of a sugar crystal.

IDUN

The idea behind the micro-containers may be compared to toffifee chocolates. The desired drug (the hazelnut) is placed into small containers (the caramel part). Hereafter, the drug is covered by a layer (chocolate), which protects it on its way through the mouth, oesophagus and stomach, all the way to the small intestine where it is assimilated by the body, and exerts its effect.

IDUN

The micro-containers are made by microfabrication techniques on silicon chips each containing 625 micro-containers.

IDUN

 

Nyheder og filtrering

Få besked om fremtidige nyheder, der matcher din filtrering.